Source [[Book - Digital Therapeutics for Mental Health and Addiction]] - Indeed, a recent comparison of research engagement with research-grade digital therapeutics to real-world engagement of digital therapeutics found that research participants were four times more likely to engage with the same technological offering than real-world consumers (Baumel, Edan, & Kane, 2019; Kelders, Kok, Ossebaard, & Van Gemert-Pijnen, 2012).